Melanizing agents are drugs that increase sensitivity to pigmentation occurs.
are synthetic psoralens. These drugs can be used either topically or orally.
The drug solution is painted on the vitiliginous lesion and exposed to sunlight for around one minute. It is then occluded by a sunscreen ointment. The treatment should be undertaken for many weeks to obtain observable results. Longer exposure to sunlight might cause blistering
of skin, so the therapy should be undertaken in the direct supervision of a physician.
It is done in alternate days. After 2 hours of taking the oral dose of 20 mg/day of a psoralen, skin is exposed to sunlight. Eyes, ears and other normally pigmented areas should be protected while spending time in the sun.
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